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4-HNE, 4-Hydroxynonenal

While alcohol consumption is perfectly fine, and even healthy, in moderation, chronic alcohol abuse is associated with increased oxidation and decreased glutathione levels

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Curr Opin BioMed Eng

Hereditary spastic paraplegia is a common phenotypic finding in ARG1 deficiency, P5CS deficiency and HHH syndrome: three inborn errors of metabolism caused by alteration of an interconnected pathway of glutamate and urea cycle metabolism